TREATMENT OF BONE DISEASE ASSOCIATED WITH BONE DEMINERALIZATION WITH BIOCORAL® AS OSTEOPOROSIS FRACTURE TREATMENT AND ITS PREVENTION
Definition of Osteoporosis
Osteoporosis and its bone complications including hip fractures have been are and will be in the future a public health problem for the major economies for the world. Because of the increased life expectancy of the population, each family had, has or will have a grandparent or close relative, fall victim to what the public health authorities do not hesitate to call as an epidemic.
Osteoporosis is a bone disease due to natural bone demineralization in which bone density decreases combined with increased bone brittleness and porosity that causes the bones to become thin and weak. It occurs mostly in women after menopause. That's because the female hormone oestrogen helps women maintain bone strength. As oestrogen levels decline, bone is lost. Osteoporosis can also occur in men. Other risk factors include: delayed puberty, poor calcium intake, smoking, excess alcohol consumption or from medications such as glucocorticoids.
Osteoporosis is often known as "the silent thief" because bone loss occurs without symptoms. As bones weaken, they are more likely to break (fracture). Hip, wrist and spine bones are at the greatest risk of breaking. The breaks in spine bones are known as vertebral co
mpression fractures, or VCFs. Left untreated, they may lead to kyphosis, commonly referred to as "dowager's hump."
Normal longitudinal femoral cut
Osteoporotic longitudinal femoral cut
According to the International Osteoporosis Foundation (www.osteofound.org), 40% of all middle-aged women (8 out of 20) and 15% of middle-aged men (3 out of 20) in Europe will suffer one or more osteoporotic fractures during their remaining lifetime. In fact, someone in Europe has a fracture every 30 seconds as a result of osteoporosis. Furthermore, they estimate that the number of osteoporosis patients will double over the next 50 years with the projected increase in the aging population and as a result of lifestyle factors. However, despite the fact that the incidence of osteoporotic fractures is growing, the problem is under-recognized with only one in two osteoporotic spinal fractures being diagnosed.
In Canada among 50-year olds, one woman out of five and one man out of eight suffers from osteoporosis. (Hanley DA, Josse RG. Prevention and management of osteoporosis: consensus statements from the Scientific Advisory Board of the Osteoporosis Society of Canada. Can Med Assoc J. 1996;155:921-3).
In all, two million Canadians suffer from osteoporosis (based on estimates made in 2006).
More than 80% of all fractures in persons over 60 are due to osteoporosis. (Goeree R, O’Brien B, Pettitt D, Cuddy L, Ferraz M, Adachi J. An assessment of the burden of illness due to osteoporosis in Canada. J Soc Obstet Gynaecol Can. 18(suppl. juillet):15-24.)
Fracture of osteoporotic bone
Osteoporotic bone fractures induce a significant risk of complications. They are mainly related to hip fractures. The usual treatments consist to reduce the fracture with an internal fixation but the osteoporotic bone fractures are often unstable that induce a late weight-bearing and increase the risks of complications related to immobility especially for elderly patient.
Hips fractures result in death in up to 20% of cases and disability in 50% of those who survive.
Osteoporotic Femoral neck, Fractured in 3 pieces
Treatment of osteoprotic fractures
Biocoral® offers an ideal treatment method for bone fractures caused by osteoporosis
Biocoral® stabilizes the fracture and can serve to heal the bones already fractured.It is proved that this biomaterial permits the body of even old persons to remake a new bone, which consequently helps to quickly repair fractures caused by osteoporosis.
Immediate postoperative radiography
Osteosynthesis of the femoral neck with
Biocoral® spheres contributing to the stabilization of the fracture. The patient is stand up at 10 days after the procedure with a total weight-bearing.
Summary of multicenter study "Hip fracture"
TREATMENT OF BONE DISEASES ASSOCIATED TO BONE DEMINERALIZATION
(PERTROCHANTERIC (HIP FRACTURE ) ASSOCIATED TO THE BONE LOSS)
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